Preclinical and clinical advances in transposon-based gene therapy

Transposons derived from Sleeping Beauty (SB), piggyBac (PB), or Tol2 typically require cotransfection of transposon DNA with a transposase either as an expression plasmid or mRNA. Consequently, this results in genomic integration of the potentially therapeutic gene into chromosomes of the desired t...

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Detalles Bibliográficos
Autores principales: Tipanee, Jaitip, Chai, Yoke Chin, VandenDriessche, Thierry, Chuah, Marinee K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715130/
https://www.ncbi.nlm.nih.gov/pubmed/29089466
http://dx.doi.org/10.1042/BSR20160614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715130/
https://www.ncbi.nlm.nih.gov/pubmed/29089466
http://dx.doi.org/10.1042/BSR20160614

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