3D genome of multiple myeloma reveals spatial genome disorganization associated with copy number variations

The Hi-C method is widely used to study the functional roles of the three-dimensional (3D) architecture of genomes. Here, we integrate Hi-C, whole-genome sequencing (WGS) and RNA-seq to study the 3D genome architecture of multiple myeloma (MM) and how it associates with genomic variation and gene ex...

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Detalles Bibliográficos
Autores principales: Wu, Pengze, Li, Tingting, Li, Ruifeng, Jia, Lumeng, Zhu, Ping, Liu, Yifang, Chen, Qing, Tang, Daiwei, Yu, Yuezhou, Li, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715138/
https://www.ncbi.nlm.nih.gov/pubmed/29203764
http://dx.doi.org/10.1038/s41467-017-01793-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715138/
https://www.ncbi.nlm.nih.gov/pubmed/29203764
http://dx.doi.org/10.1038/s41467-017-01793-w

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