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Efficient and flexible implementation of Langevin simulation for gene burst production

Gene expression involves bursts of production of both mRNA and protein, and the fluctuations in their number are increased due to such bursts. The Langevin equation is an efficient and versatile means to simulate such number fluctuation. However, how to include these mRNA and protein bursts in the L...

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Detalles Bibliográficos
Autores principales: Yan, Ching-Cher Sanders, Chepyala, Surendhar Reddy, Yen, Chao-Ming, Hsu, Chao-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715166/
https://www.ncbi.nlm.nih.gov/pubmed/29203832
http://dx.doi.org/10.1038/s41598-017-16835-y