A chimeric HS4 insulator–scaffold attachment region enhances transgene expression in transfected Chinese hamster ovary cells

Chinese hamster ovary (CHO) cells are one of the most commonly used expression systems for the production of recombinant proteins but low levels of transgene expression and transgene silencing are frequently encountered. Epigenetic regulatory elements such as the chicken β‐globin locus control regio...

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Detalles Bibliográficos
Autores principales: Chen, Si‐jia, Wang, Wen, Zhang, Feng‐yi, Jia, Yan‐long, Wang, Xiao‐yin, Guo, Xiao, Chen, Shao‐Nan, Gao, Jian‐hui, Wang, Tian‐Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715248/
https://www.ncbi.nlm.nih.gov/pubmed/29226088
http://dx.doi.org/10.1002/2211-5463.12335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715248/
https://www.ncbi.nlm.nih.gov/pubmed/29226088
http://dx.doi.org/10.1002/2211-5463.12335

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