Increasing the length and hydrophobicity of the C‐terminal sequence of transthyretin strengthens its binding affinity to retinol binding protein

Transthyretin (TTR) is a transporter for thyroid hormone (TH) and retinol, the latter via binding with retinol binding protein (RBP). Both the N‐terminal and C‐terminal regions of the TTR subunit are located in close proximity to the central binding channel for ligands. During the evolution of verte...

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Detalles Bibliográficos
Autores principales: Poodproh, Rattawan, Kaewmeechai, Supavadee, Leelawatwattana, Ladda, Prapunpoj, Porntip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715260/
https://www.ncbi.nlm.nih.gov/pubmed/29226076
http://dx.doi.org/10.1002/2211-5463.12329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715260/
https://www.ncbi.nlm.nih.gov/pubmed/29226076
http://dx.doi.org/10.1002/2211-5463.12329

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