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Antifibrotic effects of pentoxifylline improve the efficacy of gemcitabine in human pancreatic tumor xenografts

We investigated the combinatorial effects of pentoxifylline (PTX) on the efficacy of gemcitabine (GEM) in a human pancreatic tumor xenograft model. PTX significantly improved the efficacy of GEM, as shown by a 50% reduction in tumor growth rate at 4 weeks of treatment compared with that in animals g...

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Detalles Bibliográficos
Autores principales: Kim, Jung Ho, Shin, Byung Cheol, Park, Won Sang, Lee, Jaehwi, Kuh, Hyo‐Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715266/
https://www.ncbi.nlm.nih.gov/pubmed/28940685
http://dx.doi.org/10.1111/cas.13405