Cargando…

β‐Deuterium Isotope Effects on Firefly Luciferase Bioluminescence

A 5,5‐d(2)‐luciferin was prepared to measure isotope effects on reactions of two intermediates in firefly bioluminescence: emission by oxyluciferin and elimination of a putative luciferyl adenylate hydroperoxide to dehydroluciferin. A negligible isotope effect on bioluminescence provides further sup...

Descripción completa

Detalles Bibliográficos
Autores principales: Pirrung, Michael C., Dorsey, Allyson, Howitt, Natalie De, Liao, Jiayu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715289/
https://www.ncbi.nlm.nih.gov/pubmed/29226056
http://dx.doi.org/10.1002/open.201700136