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β‐Deuterium Isotope Effects on Firefly Luciferase Bioluminescence

A 5,5‐d(2)‐luciferin was prepared to measure isotope effects on reactions of two intermediates in firefly bioluminescence: emission by oxyluciferin and elimination of a putative luciferyl adenylate hydroperoxide to dehydroluciferin. A negligible isotope effect on bioluminescence provides further sup...

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Detalles Bibliográficos
Autores principales:	Pirrung, Michael C., Dorsey, Allyson, Howitt, Natalie De, Liao, Jiayu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715289/ https://www.ncbi.nlm.nih.gov/pubmed/29226056 http://dx.doi.org/10.1002/open.201700136

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