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Pyruvate kinase isozyme M2 and glutaminase might be promising molecular targets for the treatment of gastric cancer

The aim of this study was to analyze the significance of glucose metabolism‐related enzymes in the proliferation of gastric cancer under hypoxia. Four hypoxia‐resistant gastric cancer cell lines and four parent cell lines were used. Reverse transcription–PCR was used to evaluate the mRNA expression...

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Detalles Bibliográficos
Autores principales: Kitayama, Kishu, Yashiro, Masakazu, Morisaki, Tamami, Miki, Yuichiro, Okuno, Tomohisa, Kinoshita, Haruhito, Fukuoka, Tatsunari, Kasashima, Hiroaki, Masuda, Go, Hasegawa, Tsuyoshi, Sakurai, Katsunobu, Kubo, Naoshi, Hirakawa, Kosei, Ohira, Masaichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715358/
https://www.ncbi.nlm.nih.gov/pubmed/29032577
http://dx.doi.org/10.1111/cas.13421