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New Insights into the Mechanism of Action of Soluble Klotho

The klotho gene encodes a type I single-pass transmembrane protein that contains a large extracellular domain, a membrane spanning segment, and a short intracellular domain. Klotho protein exists in several forms including the full-length membrane form (mKl) and a soluble circulating form [soluble k...

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Detalles Bibliográficos
Autores principales: Dalton, George D., Xie, Jian, An, Sung-Wan, Huang, Chou-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715364/
https://www.ncbi.nlm.nih.gov/pubmed/29250031
http://dx.doi.org/10.3389/fendo.2017.00323