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Competitive Inhibitors Unveil Structure/Function Relationships in Human D-Amino Acid Oxidase
D-amino acid oxidase (DAAO) catalyzes the oxidative deamination of several neutral D-amino acids and is the enzyme mainly responsible (together with serine racemase) for degrading D-serine (D-Ser) in the central nervous system of mammals. This D-amino acid, which binds the coagonist site of the N-me...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715370/ https://www.ncbi.nlm.nih.gov/pubmed/29250527 http://dx.doi.org/10.3389/fmolb.2017.00080 |