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Inhibition of IL-18-mediated myeloid derived suppressor cell accumulation enhances anti-PD1 efficacy against osteosarcoma cancer

Myeloid derived suppressor cells (MDSC) are very important in tumor immune evasion and they dramatically increased in peripheral blood of patients with osteosarcoma cancer. The association between MDSC and various cytokines has been studied in the peripheral blood. However, little is known about the...

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Detalles Bibliográficos
Autores principales: Guan, Ying, Zhang, Rui, Peng, Zhibin, Dong, Daming, Wei, Guojun, Wang, Yansong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715437/
https://www.ncbi.nlm.nih.gov/pubmed/29226090
http://dx.doi.org/10.1016/j.jbo.2017.10.002