Paracetamol clinical dosing routine leads to paracetamol underexposure in an adult severely ill sub-Saharan African hospital population: a drug concentration measurement study

BACKGROUND: Hospitals in sub-Saharan Africa (SSA) continue to receive high numbers of severely ill (HIV-infected) patients with physical pain that may suffer from hepatic and renal dysfunction. Paracetamol is widely used for pain relief in this setting but it is unknown whether therapeutic drug conc...

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Detalles Bibliográficos
Autores principales: Bos, Jeannet C., Mistício, Mabor C., Nunguiane, Ginto, Mathôt, Ron A. A., van Hest, Reinier M., Prins, Jan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715499/
https://www.ncbi.nlm.nih.gov/pubmed/29202789
http://dx.doi.org/10.1186/s13104-017-3016-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715499/
https://www.ncbi.nlm.nih.gov/pubmed/29202789
http://dx.doi.org/10.1186/s13104-017-3016-8

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