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Choice of surrogate tissue influences neonatal EWAS findings

BACKGROUND: Epigenomes are tissue specific and thus the choice of surrogate tissue can play a critical role in interpreting neonatal epigenome-wide association studies (EWAS) and in their extrapolation to target tissue. To develop a better understanding of the link between tissue specificity and neo...

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Detalles Bibliográficos
Autores principales: Lin, Xinyi, Teh, Ai Ling, Chen, Li, Lim, Ives Yubin, Tan, Pei Fang, MacIsaac, Julia L., Morin, Alexander M., Yap, Fabian, Tan, Kok Hian, Saw, Seang Mei, Lee, Yung Seng, Holbrook, Joanna D., Godfrey, Keith M., Meaney, Michael J., Kobor, Michael S., Chong, Yap Seng, Gluckman, Peter D., Karnani, Neerja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715509/
https://www.ncbi.nlm.nih.gov/pubmed/29202839
http://dx.doi.org/10.1186/s12916-017-0970-x