Cargando…

Choice of surrogate tissue influences neonatal EWAS findings

BACKGROUND: Epigenomes are tissue specific and thus the choice of surrogate tissue can play a critical role in interpreting neonatal epigenome-wide association studies (EWAS) and in their extrapolation to target tissue. To develop a better understanding of the link between tissue specificity and neo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Xinyi, Teh, Ai Ling, Chen, Li, Lim, Ives Yubin, Tan, Pei Fang, MacIsaac, Julia L., Morin, Alexander M., Yap, Fabian, Tan, Kok Hian, Saw, Seang Mei, Lee, Yung Seng, Holbrook, Joanna D., Godfrey, Keith M., Meaney, Michael J., Kobor, Michael S., Chong, Yap Seng, Gluckman, Peter D., Karnani, Neerja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Technical Advance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715509/ https://www.ncbi.nlm.nih.gov/pubmed/29202839 http://dx.doi.org/10.1186/s12916-017-0970-x

Ejemplares similares

Developmental pathways to adiposity begin before birth and are influenced by genotype, prenatal environment and epigenome
por: Lin, Xinyi, et al.
Publicado: (2017)

Analysis of two birth tissues provides new insights into the epigenetic landscape of neonates born preterm
por: Wu, Yonghui, et al.
Publicado: (2019)

HIF3A association with adiposity: the story begins before birth
por: Pan, Hong, et al.
Publicado: (2015)

Cell type-specific DNA methylation in neonatal cord tissue and cord blood: a 850K-reference panel and comparison of cell types
por: Lin, Xinyi, et al.
Publicado: (2018)

Dichotomy in the Impact of Elevated Maternal Glucose Levels on Neonatal Epigenome
por: Lim, Ives Yubin, et al.
Publicado: (2021)

Comparison of Methyl-capture Sequencing vs. Infinium 450K methylation array for methylome analysis in clinical samples
por: Teh, Ai Ling, et al.
Publicado: (2016)

Variability in newborn telomere length is explained by inheritance and intrauterine environment
por: Chen, Li, et al.
Publicado: (2022)

Maternal Blood Pressure During Pregnancy and Early Childhood Blood Pressures in the Offspring: The GUSTO Birth Cohort Study
por: Lim, Wai-Yee, et al.
Publicado: (2015)

Determinants of cord blood adipokines and association with neonatal abdominal adipose tissue distribution
por: Tan, Karen, et al.
Publicado: (2021)

Predictors of screen viewing time in young Singaporean children: the GUSTO cohort
por: Bernard, Jonathan Y., et al.
Publicado: (2017)

The association between maternal blood pressures and offspring size at birth in Southeast Asian women
por: Lim, Wai-Yee, et al.
Publicado: (2014)

Body mass index trajectories in the first two years and subsequent childhood cardio-metabolic outcomes: a prospective multi-ethnic Asian cohort study
por: Aris, Izzuddin M., et al.
Publicado: (2017)

Integrative multi-omics database (iMOMdb) of Asian pregnant women
por: Pan, Hong, et al.
Publicado: (2022)

Effects of Antenatal Maternal Depressive Symptoms and Socio-Economic Status on Neonatal Brain Development are Modulated by Genetic Risk
por: Qiu, Anqi, et al.
Publicado: (2017)

Genetic Link Determining the Maternal-Fetal Circulation of Vitamin D
por: Sampathkumar, Aparna, et al.
Publicado: (2021)

The effect of genotype and in utero environment on interindividual variation in neonate DNA methylomes
por: Teh, Ai Ling, et al.
Publicado: (2014)

Neonatal amygdala microstructure mediates the relationship between gestational glycemia and offspring adiposity
por: Cai, Shirong, et al.
Publicado: (2021)

Associations of Maternal Retinal Vasculature with Subsequent Fetal Growth and Birth Size
por: Li, Ling-Jun, et al.
Publicado: (2015)

Ethnic differences translate to inadequacy of high-risk screening for gestational diabetes mellitus in an Asian population: a cohort study
por: Chong, Yap-Seng, et al.
Publicado: (2014)

Maternal Lutein and Zeaxanthin Concentrations in Relation to Offspring Visual Acuity at 3 Years of Age: The GUSTO Study
por: Lai, Jun S., et al.
Publicado: (2020)

Plasma lipidomic profiling reveals metabolic adaptations to pregnancy and signatures of cardiometabolic risk: a preconception and longitudinal cohort study
por: Chen, Li, et al.
Publicado: (2023)

Infant dietary patterns and early childhood caries in a multi-ethnic Asian cohort
por: Hu, Shijia, et al.
Publicado: (2019)

Associations of infant milk feed type on early postnatal growth of offspring exposed and unexposed to gestational diabetes in utero
por: Aris, Izzuddin M., et al.
Publicado: (2015)

Gestational diabetes mellitus and retinal microvasculature
por: Li, Ling-Jun, et al.
Publicado: (2017)

Machine Learning–Derived Prenatal Predictive Risk Model to Guide Intervention and Prevent the Progression of Gestational Diabetes Mellitus to Type 2 Diabetes: Prediction Model Development Study
por: Kumar, Mukkesh, et al.
Publicado: (2022)

Singaporean Mothers’ Perception of Their Three-year-old Child’s Weight Status: A Cross-Sectional Study
por: Cheng, Tuck Seng, et al.
Publicado: (2016)

Automated Machine Learning (AutoML)-Derived Preconception Predictive Risk Model to Guide Early Intervention for Gestational Diabetes Mellitus
por: Kumar, Mukkesh, et al.
Publicado: (2022)

Association of Maternal Vitamin D Status with Glucose Tolerance and Caesarean Section in a Multi-Ethnic Asian Cohort: The Growing Up in Singapore Towards Healthy Outcomes Study
por: Loy, See Ling, et al.
Publicado: (2015)

Population Differences in Brain Morphology and Microstructure among Chinese, Malay, and Indian Neonates
por: Bai, Jordan, et al.
Publicado: (2012)

Association of Elective and Emergency Cesarean Delivery With Early Childhood Overweight at 12 Months of Age
por: Cai, Meijin, et al.
Publicado: (2018)

Rate of establishing the gut microbiota in infancy has consequences for future health
por: Dogra, Shaillay, et al.
Publicado: (2015)

Transcriptome Changes Affecting Hedgehog and Cytokine Signalling in the Umbilical Cord: Implications for Disease Risk
por: Stünkel, Walter, et al.
Publicado: (2012)

Integration of DNA methylation patterns and genetic variation in human pediatric tissues help inform EWAS design and interpretation
por: Islam, Sumaiya A., et al.
Publicado: (2019)

The placental lipidome of maternal antenatal depression predicts socio-emotional problems in the offspring
por: Wong, Gerard, et al.
Publicado: (2021)

Fetal sex-specific epigenetic associations with prenatal maternal depressive symptoms
por: Kee, Michelle Z.L., et al.
Publicado: (2022)

Relations of Plasma Polyunsaturated Fatty Acids With Blood Pressures During the 26th and 28th Week of Gestation in Women of Chinese, Malay, and Indian Ethnicity
por: Lim, Wai-Yee, et al.
Publicado: (2015)

Allergic sensitization trajectories to age 8 years in the Singapore GUSTO cohort()
por: Lau, Hui Xing, et al.
Publicado: (2022)

Brown Adipose Tissue, Adiposity, and Metabolic Profile in Preschool Children
por: Tint, Mya Thway, et al.
Publicado: (2021)

Ethnic diversity in infant gut microbiota is apparent before the introduction of complementary diets
por: Xu, Jia, et al.
Publicado: (2020)

The Influence of Gestational Diabetes on Neurodevelopment of Children in the First Two Years of Life: A Prospective Study
por: Cai, Shirong, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_a470ri6gd05qerd96cam7qthsl