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Role of matrix metalloproteinase-2/9 (MMP2/9) in lead-induced changes in an in vitro blood-brain barrier model

Lead (Pb) is a well-known neurotoxicant and a risk factor for neurologic disorders. The blood brain barrier (BBB) plays an important role in the maintenance of optimal brain function. BBB is a target of Pb, and studies have shown that Pb induced barrier loss and decreased the expression of tight jun...

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Detalles Bibliográficos
Autores principales: Liu, Xinqin, Su, Peng, Meng, Shanshan, Aschner, Michael, Cao, Yupeng, Luo, Wenjing, Zheng, Gang, Liu, Mingchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715519/
https://www.ncbi.nlm.nih.gov/pubmed/29209140
http://dx.doi.org/10.7150/ijbs.20670