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Is systems pharmacology ready to impact upon therapy development? A study on the cholesterol biosynthesis pathway

BACKGROUND AND PURPOSE: An ever‐growing wealth of information on current drugs and their pharmacological effects is available from online databases. As our understanding of systems biology increases, we have the opportunity to predict, model and quantify how drug combinations can be introduced that...

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Detalles Bibliográficos
Autores principales: Benson, Helen E, Watterson, Steven, Sharman, Joanna L, Mpamhanga, Chido P, Parton, Andrew, Southan, Christopher, Harmar, Anthony J, Ghazal, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715582/
https://www.ncbi.nlm.nih.gov/pubmed/28910500
http://dx.doi.org/10.1111/bph.14037