Resident macrophages of pancreatic islets have a seminal role in the initiation of autoimmune diabetes of NOD mice

Treatment of C57BL/6 or NOD mice with a monoclonal antibody to the CSF-1 receptor resulted in depletion of the resident macrophages of pancreatic islets of Langerhans that lasted for several weeks. Depletion of macrophages in C57BL/6 mice did not affect multiple parameters of islet function, includi...

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Detalles Bibliográficos
Autores principales: Carrero, Javier A., McCarthy, Derrick P., Ferris, Stephen T., Wan, Xiaoxiao, Hu, Hao, Zinselmeyer, Bernd H., Vomund, Anthony N., Unanue, Emil R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2017
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715775/
https://www.ncbi.nlm.nih.gov/pubmed/29133420
http://dx.doi.org/10.1073/pnas.1713543114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715775/
https://www.ncbi.nlm.nih.gov/pubmed/29133420
http://dx.doi.org/10.1073/pnas.1713543114

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