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Resident macrophages of pancreatic islets have a seminal role in the initiation of autoimmune diabetes of NOD mice
Treatment of C57BL/6 or NOD mice with a monoclonal antibody to the CSF-1 receptor resulted in depletion of the resident macrophages of pancreatic islets of Langerhans that lasted for several weeks. Depletion of macrophages in C57BL/6 mice did not affect multiple parameters of islet function, includi...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715775/ https://www.ncbi.nlm.nih.gov/pubmed/29133420 http://dx.doi.org/10.1073/pnas.1713543114 |