Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein

Acquired resistance against antimalarial drugs has further increased the need for an effective malaria vaccine. The current leading candidate, RTS,S, is a recombinant circumsporozoite protein (CSP)-based vaccine against Plasmodium falciparum that contains 19 NANP repeats followed by a thrombospondin...

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Detalles Bibliográficos
Autores principales: Oyen, David, Torres, Jonathan L., Wille-Reece, Ulrike, Ockenhouse, Christian F., Emerling, Daniel, Glanville, Jacob, Volkmuth, Wayne, Flores-Garcia, Yevel, Zavala, Fidel, Ward, Andrew B., King, C. Richter, Wilson, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2017
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715787/
https://www.ncbi.nlm.nih.gov/pubmed/29138320
http://dx.doi.org/10.1073/pnas.1715812114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715787/
https://www.ncbi.nlm.nih.gov/pubmed/29138320
http://dx.doi.org/10.1073/pnas.1715812114

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