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The structural basis of ryanodine receptor ion channel function

Large-conductance Ca(2+) release channels known as ryanodine receptors (RyRs) mediate the release of Ca(2+) from an intracellular membrane compartment, the endo/sarcoplasmic reticulum. There are three mammalian RyR isoforms: RyR1 is present in skeletal muscle; RyR2 is in heart muscle; and RyR3 is ex...

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Detalles Bibliográficos
Autor principal: Meissner, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715910/
https://www.ncbi.nlm.nih.gov/pubmed/29122978
http://dx.doi.org/10.1085/jgp.201711878