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A common mechanism for CFTR potentiators

Cystic fibrosis (CF) is a channelopathy caused by loss-of-function mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which encodes a phosphorylation-activated and adenosine triphosphate (ATP)–gated chloride channel. In the past few years, high-throughput drug screenin...

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Detalles Bibliográficos
Autores principales: Yeh, Han-I, Sohma, Yoshiro, Conrath, Katja, Hwang, Tzyh-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715911/
https://www.ncbi.nlm.nih.gov/pubmed/29079713
http://dx.doi.org/10.1085/jgp.201711886