The methyltransferase NSD3 promotes antiviral innate immunity via direct lysine methylation of IRF3

Lysine methylation is an important posttranslational modification, implicated in various biological pathological conditions. The transcription factor interferon regulatory factor 3 (IRF3) is essential for antiviral innate immunity, yet the mechanism for methylation control of IRF3 activation remains...

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Detalles Bibliográficos
Autores principales: Wang, Chunmei, Wang, Qinlan, Xu, Xiaoqing, Xie, Bin, Zhao, Yong, Li, Nan, Cao, Xuetao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716042/
https://www.ncbi.nlm.nih.gov/pubmed/29101251
http://dx.doi.org/10.1084/jem.20170856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716042/
https://www.ncbi.nlm.nih.gov/pubmed/29101251
http://dx.doi.org/10.1084/jem.20170856

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