SORLA attenuates EphA4 signaling and amyloid β–induced neurodegeneration

Sortilin-related receptor with LDLR class A repeats (SORLA, SORL1, or LR11) is a genetic risk factor associated with Alzheimer’s disease (AD). Although SORLA is known to regulate trafficking of the amyloid β (Aβ) precursor protein to decrease levels of proteotoxic Aβ oligomers, whether SORLA can cou...

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Detalles Bibliográficos
Autores principales: Huang, Timothy Y., Zhao, Yingjun, Jiang, Lu-lin, Li, Xiaoguang, Liu, Yan, Sun, Yu, Piña-Crespo, Juan C., Zhu, Bing, Masliah, Eliezer, Willnow, Thomas E., Pasquale, Elena B., Xu, Huaxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716044/
https://www.ncbi.nlm.nih.gov/pubmed/29114064
http://dx.doi.org/10.1084/jem.20171413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716044/
https://www.ncbi.nlm.nih.gov/pubmed/29114064
http://dx.doi.org/10.1084/jem.20171413

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