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A role for astroglia in prion diseases

In this issue of JEM, Krejciova et al. (https://doi.org/10.1084/jem.20161547) report that astrocytes derived from human iPSCs can replicate human CJD prions. These observations provide a new, potentially very valuable model for studying human prions in cellula and for identifying antiprion compounds...

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Detalles Bibliográficos
Autores principales: Aguzzi, Adriano, Liu, Yingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716049/
https://www.ncbi.nlm.nih.gov/pubmed/29162644
http://dx.doi.org/10.1084/jem.20172045