Deep learning of the splicing (epi)genetic code reveals a novel candidate mechanism linking histone modifications to ESC fate decision

Alternative splicing (AS) is a genetically and epigenetically regulated pre-mRNA processing to increase transcriptome and proteome diversity. Comprehensively decoding these regulatory mechanisms holds promise in getting deeper insights into a variety of biological contexts involving in AS, such as d...

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Detalles Bibliográficos
Autores principales: Xu, Yungang, Wang, Yongcui, Luo, Jiesi, Zhao, Weiling, Zhou, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716079/
https://www.ncbi.nlm.nih.gov/pubmed/29036709
http://dx.doi.org/10.1093/nar/gkx870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716079/
https://www.ncbi.nlm.nih.gov/pubmed/29036709
http://dx.doi.org/10.1093/nar/gkx870

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