A mechanism underlying position-specific regulation of alternative splicing

Many RNA-binding proteins including a master regulator of splicing in developing brain and muscle, polypyrimidine tract-binding protein 1 (PTBP1), can either activate or repress alternative exons depending on the pre-mRNA recruitment position. When bound upstream or within regulated exons PTBP1 tend...

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Detalles Bibliográficos
Autores principales: Hamid, Fursham M., Makeyev, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716086/
https://www.ncbi.nlm.nih.gov/pubmed/30053257
http://dx.doi.org/10.1093/nar/gkx901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716086/
https://www.ncbi.nlm.nih.gov/pubmed/30053257
http://dx.doi.org/10.1093/nar/gkx901

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