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Molecular mechanism of DNA association with single-stranded DNA binding protein

During DNA replication, the single-stranded DNA binding protein (SSB) wraps single-stranded DNA (ssDNA) with high affinity to protect it from degradation and prevent secondary structure formation. Although SSB binds ssDNA tightly, it can be repositioned along ssDNA to follow the advancement of the r...

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Detalles Bibliográficos
Autores principales: Maffeo, Christopher, Aksimentiev, Aleksei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716091/
https://www.ncbi.nlm.nih.gov/pubmed/29059392
http://dx.doi.org/10.1093/nar/gkx917