A structural basis for the antibiotic resistance conferred by an N1-methylation of A1408 in 16S rRNA

The aminoglycoside resistance conferred by an N1-methylation of A1408 in 16S rRNA by a novel plasmid-mediated methyltransferase NpmA can be a future health threat. In the present study, we have determined crystal structures of the bacterial ribosomal decoding A site with an A1408m(1)A antibiotic-res...

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Detalles Bibliográficos
Autores principales: Kanazawa, Hiroki, Baba, Fumika, Koganei, Mai, Kondo, Jiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716097/
https://www.ncbi.nlm.nih.gov/pubmed/29036479
http://dx.doi.org/10.1093/nar/gkx882

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716097/
https://www.ncbi.nlm.nih.gov/pubmed/29036479
http://dx.doi.org/10.1093/nar/gkx882

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