Striatal N-Acetylaspartate Synthetase Shati/Nat8l Regulates Depression-Like Behaviors via mGluR3-Mediated Serotonergic Suppression in Mice

BACKGROUND: Several clinical studies have suggested that N-acetylaspartate and N-acetylaspartylglutamate levels in the human brain are associated with various psychiatric disorders, including major depressive disorder. We have previously identified Shati/Nat8l, an N-acetyltransferase, in the brain u...

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Detalles Bibliográficos
Autores principales: Miyamoto, Yoshiaki, Iegaki, Noriyuki, Fu, Kequan, Ishikawa, Yudai, Sumi, Kazuyuki, Azuma, Sota, Uno, Kyosuke, Muramatsu, Shin-ichi, Nitta, Atsumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Regular Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716104/
https://www.ncbi.nlm.nih.gov/pubmed/29020418
http://dx.doi.org/10.1093/ijnp/pyx078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716104/
https://www.ncbi.nlm.nih.gov/pubmed/29020418
http://dx.doi.org/10.1093/ijnp/pyx078

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