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Striatal N-Acetylaspartate Synthetase Shati/Nat8l Regulates Depression-Like Behaviors via mGluR3-Mediated Serotonergic Suppression in Mice

BACKGROUND: Several clinical studies have suggested that N-acetylaspartate and N-acetylaspartylglutamate levels in the human brain are associated with various psychiatric disorders, including major depressive disorder. We have previously identified Shati/Nat8l, an N-acetyltransferase, in the brain u...

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Detalles Bibliográficos
Autores principales:	Miyamoto, Yoshiaki, Iegaki, Noriyuki, Fu, Kequan, Ishikawa, Yudai, Sumi, Kazuyuki, Azuma, Sota, Uno, Kyosuke, Muramatsu, Shin-ichi, Nitta, Atsumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Regular Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716104/ https://www.ncbi.nlm.nih.gov/pubmed/29020418 http://dx.doi.org/10.1093/ijnp/pyx078

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