The REMOTE-control system: a system for reversible and tunable control of endogenous gene expression in mice

We report here a robust, tunable, and reversible transcription control system for endogenous genes. The REMOTE-control system (Reversible Manipulation of Transcription at Endogenous loci) employs enhanced lac repression and tet activation systems. With this approach, we show in mouse embryonic stem...

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Detalles Bibliográficos
Autores principales: Lee, Kwang-Ho, Oghamian, Shirley, Park, Jin-A, Kang, Liang, Laird, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716148/
https://www.ncbi.nlm.nih.gov/pubmed/28981717
http://dx.doi.org/10.1093/nar/gkx829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716148/
https://www.ncbi.nlm.nih.gov/pubmed/28981717
http://dx.doi.org/10.1093/nar/gkx829

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