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AAV2-Mediated Transduction of the Mouse Retina After Optic Nerve Injury
PURPOSE: Gene therapy of retinal ganglion cells (RGCs) has promise as a powerful therapeutic for the rescue and regeneration of these cells after optic nerve damage. However, early after damage, RGCs undergo atrophic changes, including gene silencing. It is not known if these changes will deleteriou...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716181/ https://www.ncbi.nlm.nih.gov/pubmed/29204649 http://dx.doi.org/10.1167/iovs.17-22634 |