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AAV2-Mediated Transduction of the Mouse Retina After Optic Nerve Injury

PURPOSE: Gene therapy of retinal ganglion cells (RGCs) has promise as a powerful therapeutic for the rescue and regeneration of these cells after optic nerve damage. However, early after damage, RGCs undergo atrophic changes, including gene silencing. It is not known if these changes will deleteriou...

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Detalles Bibliográficos
Autores principales:	Nickells, Robert W., Schmitt, Heather M., Maes, Margaret E., Schlamp, Cassandra L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2017
Materias:	Glaucoma
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716181/ https://www.ncbi.nlm.nih.gov/pubmed/29204649 http://dx.doi.org/10.1167/iovs.17-22634

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