Characterization of the APLF FHA–XRCC1 phosphopeptide interaction and its structural and functional implications

Aprataxin and PNKP-like factor (APLF) is a DNA repair factor containing a forkhead-associated (FHA) domain that supports binding to the phosphorylated FHA domain binding motifs (FBMs) in XRCC1 and XRCC4. We have characterized the interaction of the APLF FHA domain with phosphorylated XRCC1 peptides...

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Detalles Bibliográficos
Autores principales: Kim, Kyungmin, Pedersen, Lars C., Kirby, Thomas W., DeRose, Eugene F., London, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716189/
https://www.ncbi.nlm.nih.gov/pubmed/29059378
http://dx.doi.org/10.1093/nar/gkx941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716189/
https://www.ncbi.nlm.nih.gov/pubmed/29059378
http://dx.doi.org/10.1093/nar/gkx941

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