Genome-wide prediction of minor-groove electrostatic potential enables biophysical modeling of protein–DNA binding

Protein–DNA binding is a fundamental component of gene regulatory processes, but it is still not completely understood how proteins recognize their target sites in the genome. Besides hydrogen bonding in the major groove (base readout), proteins recognize minor-groove geometry using positively charg...

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Detalles Bibliográficos
Autores principales: Chiu, Tsu-Pei, Rao, Satyanarayan, Mann, Richard S., Honig, Barry, Rohs, Remo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716191/
https://www.ncbi.nlm.nih.gov/pubmed/29040720
http://dx.doi.org/10.1093/nar/gkx915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716191/
https://www.ncbi.nlm.nih.gov/pubmed/29040720
http://dx.doi.org/10.1093/nar/gkx915

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