PtdIns3P controls mTORC1 signaling through lysosomal positioning

The mechanistic target of rapamycin complex 1 (mTORC1) is a protein kinase complex that localizes to lysosomes to up-regulate anabolic processes and down-regulate autophagy. Although mTORC1 is known to be activated by lysosome positioning and by amino acid–stimulated production of phosphatidylinosit...

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Detalles Bibliográficos
Autores principales: Hong, Zhi, Pedersen, Nina Marie, Wang, Ling, Torgersen, Maria Lyngaas, Stenmark, Harald, Raiborg, Camilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716264/
https://www.ncbi.nlm.nih.gov/pubmed/29030394
http://dx.doi.org/10.1083/jcb.201611073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716264/
https://www.ncbi.nlm.nih.gov/pubmed/29030394
http://dx.doi.org/10.1083/jcb.201611073

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