BAG3 directly stabilizes Hexokinase 2 mRNA and promotes aerobic glycolysis in pancreatic cancer cells

Aerobic glycolysis, a phenomenon known historically as the Warburg effect, is one of the hallmarks of cancer cells. In this study, we characterized the role of BAG3 in aerobic glycolysis of pancreatic ductal adenocarcinoma (PDAC) and its molecular mechanisms. Our data show that aberrant expression o...

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Detalles Bibliográficos
Autores principales: An, Ming-Xin, Li, Si, Yao, Han-Bing, Li, Chao, Wang, Jia-Mei, Sun, Jia, Li, Xin-Yu, Meng, Xiao-Na, Wang, Hua-Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716268/
https://www.ncbi.nlm.nih.gov/pubmed/29114069
http://dx.doi.org/10.1083/jcb.201701064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716268/
https://www.ncbi.nlm.nih.gov/pubmed/29114069
http://dx.doi.org/10.1083/jcb.201701064

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