Type I interferon enhances necroptosis of Salmonella Typhimurium–infected macrophages by impairing antioxidative stress responses

Salmonella enterica serovar Typhimurium exploits the host’s type I interferon (IFN-I) response to induce receptor-interacting protein (RIP) kinase–mediated necroptosis in macrophages. However, the events that drive necroptosis execution downstream of IFN-I and RIP signaling remain elusive. In this s...

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Detalles Bibliográficos
Autores principales: Hos, Nina Judith, Ganesan, Raja, Gutiérrez, Saray, Hos, Deniz, Klimek, Jennifer, Abdullah, Zeinab, Krönke, Martin, Robinson, Nirmal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716270/
https://www.ncbi.nlm.nih.gov/pubmed/29055012
http://dx.doi.org/10.1083/jcb.201701107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716270/
https://www.ncbi.nlm.nih.gov/pubmed/29055012
http://dx.doi.org/10.1083/jcb.201701107

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