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Fanconi anemia FANCD2 and FANCI proteins regulate the nuclear dynamics of splicing factors

Proteins disabled in the cancer-prone disorder Fanconi anemia (FA) ensure the maintenance of chromosomal stability during DNA replication. FA proteins regulate replication dynamics, coordinate replication-coupled repair of interstrand DNA cross-links, and mitigate conflicts between replication and t...

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Detalles Bibliográficos
Autores principales: Moriel-Carretero, María, Ovejero, Sara, Gérus-Durand, Marie, Vryzas, Dimos, Constantinou, Angelos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716273/
https://www.ncbi.nlm.nih.gov/pubmed/29030393
http://dx.doi.org/10.1083/jcb.201702136