Cargando…

Fanconi anemia FANCD2 and FANCI proteins regulate the nuclear dynamics of splicing factors

Proteins disabled in the cancer-prone disorder Fanconi anemia (FA) ensure the maintenance of chromosomal stability during DNA replication. FA proteins regulate replication dynamics, coordinate replication-coupled repair of interstrand DNA cross-links, and mitigate conflicts between replication and t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Moriel-Carretero, María, Ovejero, Sara, Gérus-Durand, Marie, Vryzas, Dimos, Constantinou, Angelos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716273/ https://www.ncbi.nlm.nih.gov/pubmed/29030393 http://dx.doi.org/10.1083/jcb.201702136

Ejemplares similares

Defective FANCI Binding by a Fanconi Anemia-Related FANCD2 Mutant
por: Sato, Koichi, et al.
Publicado: (2014)

Phosphorylation of FANCD2 Inhibits the FANCD2/FANCI Complex and Suppresses the Fanconi Anemia Pathway in the Absence of DNA Damage
por: Lopez-Martinez, David, et al.
Publicado: (2019)

Fanconi anemia proteins FANCD2 and FANCI exhibit different DNA damage responses during S-phase
por: Sareen, Archana, et al.
Publicado: (2012)

Monoubiquitination by the human Fanconi anemia core complex clamps FANCI:FANCD2 on DNA in filamentous arrays
por: Tan, Winnie, et al.
Publicado: (2020)

Coordinate Nuclear Targeting of the FANCD2 and FANCI Proteins via a FANCD2 Nuclear Localization Signal
por: Boisvert, Rebecca A., et al.
Publicado: (2013)

Fanconi anemia pathway regulation by FANCI in prostate cancer
por: Kaljunen, Heidi, et al.
Publicado: (2023)

Structural insight into FANCI–FANCD2 monoubiquitination
por: Li, Landing, et al.
Publicado: (2020)

The 13th Fanconi Anemia Gene Identified: FANCI – Importance of the ‘Fanconi Anemia Pathway’ for Cellular Oncology
por: Meijer, Gerrit A.
Publicado: (2007)

Identification of the Fanconi Anemia Complementation Group I Gene, FANCI
por: Dorsman, Josephine C., et al.
Publicado: (2007)

A Fanci knockout mouse model reveals common and distinct functions for FANCI and FANCD2
por: Dubois, Emilie L, et al.
Publicado: (2019)

Regulation of FANCD2 and FANCI monoubiquitination by their interaction and by DNA
por: Longerich, Simonne, et al.
Publicado: (2014)

The FANCD2–FANCI complex is recruited to DNA interstrand crosslinks before monoubiquitination of FANCD2
por: Liang, Chih-Chao, et al.
Publicado: (2016)

Dysfunctional telomeres in primary cells from Fanconi anemia FANCD2 patients
por: Joksic, Ivana, et al.
Publicado: (2012)

DNA robustly stimulates FANCD2 monoubiquitylation in the complex with FANCI
por: Sato, Koichi, et al.
Publicado: (2012)

Structural and biochemical basis of interdependent FANCI‐FANCD2 ubiquitination
por: Lemonidis, Kimon, et al.
Publicado: (2022)

Binding of FANCI-FANCD2 Complex to RNA and R-Loops Stimulates Robust FANCD2 Monoubiquitination
por: Liang, Zhuobin, et al.
Publicado: (2019)

FANCD2–FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair
por: Alcón, Pablo, et al.
Publicado: (2020)

Direct Inhibition of TNF-α Promoter Activity by Fanconi Anemia Protein FANCD2
por: Matsushita, Nobuko, et al.
Publicado: (2011)

FANCI Protein Binds to DNA and Interacts with FANCD2 to Recognize Branched Structures
por: Yuan, Fenghua, et al.
Publicado: (2009)

ATR-Mediated FANCI Phosphorylation Regulates Both Ubiquitination and Deubiquitination of FANCD2
por: Tan, Winnie, et al.
Publicado: (2020)

Fanconi anemia protein FANCD2 is activated by AICAR, a modulator of AMPK and cellular energy metabolism
por: Chun, Min Jeong, et al.
Publicado: (2017)

Differential functions of FANCI and FANCD2 ubiquitination stabilize ID2 complex on DNA
por: Rennie, Martin L, et al.
Publicado: (2020)

UHRF1 Is a Sensor for DNA Interstrand Crosslinks and Recruits FANCD2 to Initiate the Fanconi Anemia Pathway
por: Liang, Chih-Chao, et al.
Publicado: (2015)

DNAH2 facilitates the homologous recombination repair of Fanconi anemia pathway through modulating FANCD2 ubiquitination
por: Chang, Lixian, et al.
Publicado: (2021)

FANCD2 regulates BLM complex functions independently of FANCI to promote replication fork recovery
por: Chaudhury, Indrajit, et al.
Publicado: (2013)

FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2
por: Castella, Maria, et al.
Publicado: (2015)

Monoubiquitinated Fanconi Anemia D2 (FANCD2-Ub) Is Required for BCR-ABL1 Kinase -Induced Leukemogenesis
por: Koptyra, Mateusz, et al.
Publicado: (2011)

Cells Deficient in the Fanconi Anemia Protein FANCD2 are Hypersensitive to the Cytotoxicity and DNA Damage Induced by Coffee and Caffeic Acid
por: Burgos-Morón, Estefanía, et al.
Publicado: (2016)

Rescue of replication failure by Fanconi anaemia proteins
por: Constantinou, Angelos
Publicado: (2011)

FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response
por: Thompson, Elizabeth L., et al.
Publicado: (2017)

The Alkylating Agent Methyl Methanesulfonate Triggers Lipid Alterations at the Inner Nuclear Membrane That Are Independent from Its DNA-Damaging Ability
por: Ovejero, Sara, et al.
Publicado: (2021)

Fanconi anemia protein FANCD2 inhibits TRF1 polyADP-ribosylation through tankyrase1-dependent manner
por: Lyakhovich, Alex, et al.
Publicado: (2011)

Lymphopenia With Clinical and Laboratory Features of Combined Immune Deficiency in an 11-Year-Old Female With FANCD2 Variants and Fanconi Anemia
por: Deniskin, Roman, et al.
Publicado: (2019)

Dysfunctional DNA repair pathway via defective FANCD2 gene engenders multifarious exomic and transcriptomic effects in Fanconi anemia
por: Velmurugan, Karthik Raja, et al.
Publicado: (2018)

A sterol‐PI(4)P exchanger modulates the Tel1/ATM axis of the DNA damage response
por: Ovejero, Sara, et al.
Publicado: (2023)

FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5′-DNA end
por: Sato, Koichi, et al.
Publicado: (2016)

The FA Core Complex Contains a Homo-dimeric Catalytic Module for the Symmetric Mono-ubiquitination of FANCI-FANCD2
por: Swuec, Paolo, et al.
Publicado: (2016)

Inactivation of ribosomal protein S27-like impairs DNA interstrand cross-link repair by destabilization of FANCD2 and FANCI
por: Sun, Siyuan, et al.
Publicado: (2020)

Mutated Fanconi anemia pathway in non-Fanconi anemia cancers
por: Shen, Yihang, et al.
Publicado: (2015)

High-risk human papillomavirus oncogenes disrupt the Fanconi anemia DNA repair pathway by impairing localization and de-ubiquitination of FancD2
por: Khanal, Sujita, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_19pbli18av9i03bsmdd9vl7ggc