An apicosome initiates self-organizing morphogenesis of human pluripotent stem cells

Human pluripotent stem cells (hPSCs) self-organize into apicobasally polarized cysts, reminiscent of the lumenal epiblast stage, providing a model to explore key morphogenic processes in early human embryos. Here, we show that apical polarization begins on the interior of single hPSCs through the dy...

Descripción completa

Detalles Bibliográficos
Autores principales: Taniguchi, Kenichiro, Shao, Yue, Townshend, Ryan F., Cortez, Chari L., Harris, Clair E., Meshinchi, Sasha, Kalantry, Sundeep, Fu, Jianping, O’Shea, K. Sue, Gumucio, Deborah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716285/
https://www.ncbi.nlm.nih.gov/pubmed/29021220
http://dx.doi.org/10.1083/jcb.201704085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716285/
https://www.ncbi.nlm.nih.gov/pubmed/29021220
http://dx.doi.org/10.1083/jcb.201704085

Ejemplares similares