Cargando…

An apicosome initiates self-organizing morphogenesis of human pluripotent stem cells

Human pluripotent stem cells (hPSCs) self-organize into apicobasally polarized cysts, reminiscent of the lumenal epiblast stage, providing a model to explore key morphogenic processes in early human embryos. Here, we show that apical polarization begins on the interior of single hPSCs through the dy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Taniguchi, Kenichiro, Shao, Yue, Townshend, Ryan F., Cortez, Chari L., Harris, Clair E., Meshinchi, Sasha, Kalantry, Sundeep, Fu, Jianping, O’Shea, K. Sue, Gumucio, Deborah L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716285/ https://www.ncbi.nlm.nih.gov/pubmed/29021220 http://dx.doi.org/10.1083/jcb.201704085

Ejemplares similares

Effect of Cell Spreading on Rosette Formation by Human Pluripotent Stem Cell-Derived Neural Progenitor Cells
por: Townshend, Ryan F., et al.
Publicado: (2020)

Lumen Formation Is an Intrinsic Property of Isolated Human Pluripotent Stem Cells
por: Taniguchi, Kenichiro, et al.
Publicado: (2015)

A pluripotent stem cell-based model for post-implantation human amniotic sac development
por: Shao, Yue, et al.
Publicado: (2017)

Self-organized amniogenesis by human pluripotent stem cells in a biomimetic implantation-like niche
por: Shao, Yue, et al.
Publicado: (2016)

Apical polarization and lumenogenesis: The apicosome sheds new light
por: Romero-Morales, Alejandra I., et al.
Publicado: (2017)

Spatially resolved cell polarity proteomics of a human epiblast model
por: Wang, Sicong, et al.
Publicado: (2021)

Apicosome: Newly identified cell-type-specific organelle in mouse cochlear and vestibular hair cells
por: Li, Xiaofen, et al.
Publicado: (2023)

Opening the black box: Stem cell–based modeling of human post-implantation development
por: Taniguchi, Kenichiro, et al.
Publicado: (2019)

PRC2 represses transcribed genes on the imprinted inactive X chromosome in mice
por: Maclary, Emily, et al.
Publicado: (2017)

Conversion of random X-inactivation to imprinted X-inactivation by maternal PRC2
por: Harris, Clair, et al.
Publicado: (2019)

Differentiation-dependent Requirement of Tsix long non-coding RNA in Imprinted X-chromosome Inactivation
por: Maclary, Emily, et al.
Publicado: (2014)

The Polycomb Group Protein EED Is Dispensable for the Initiation of Random X-Chromosome Inactivation
por: Kalantry, Sundeep, et al.
Publicado: (2006)

An Xist-activating antisense RNA required for X-chromosome inactivation
por: Sarkar, Mrinal K., et al.
Publicado: (2015)

Pluripotent state transitions coordinate morphogenesis in mouse and human embryos
por: Shahbazi, Marta N., et al.
Publicado: (2017)

Embryo size regulates the timing and mechanism of pluripotent tissue morphogenesis
por: Orietti, Lorenzo C., et al.
Publicado: (2020)

Self-Organizing Properties of Mouse Pluripotent Cells Initiate Morphogenesis upon Implantation
por: Bedzhov, Ivan, et al.
Publicado: (2014)

Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation
por: Kalantry, Sundeep, et al.
Publicado: (2009)

Activation of Xist by an evolutionarily conserved function of KDM5C demethylase
por: Samanta, Milan Kumar, et al.
Publicado: (2022)

Dysregulation of protein synthesis and dendritic spine morphogenesis in ASD: studies in human pluripotent stem cells
por: Lo, Louisa Hoi-Ying, et al.
Publicado: (2020)

Integrin β1 coordinates survival and morphogenesis of the embryonic lineage upon implantation and pluripotency transition
por: Molè, Matteo Amitaba, et al.
Publicado: (2021)

Biochemistry and Morphogenesis
por: Stone, L. S.
Publicado: (1943)

The Polycomb group protein Eed protects the inactive X-chromosome from differentiation-induced reactivation
por: Kalantry, Sundeep, et al.
Publicado: (2006)

Deep neural net tracking of human pluripotent stem cells reveals intrinsic behaviors directing morphogenesis
por: Joy, David A., et al.
Publicado: (2021)

A monoallelic-to-biallelic T-cell transcriptional switch regulates GATA3 abundance
por: Ku, Chia-Jui, et al.
Publicado: (2015)

Pluripotency Factors on Their Lineage Move
por: Weidgang, Clair E., et al.
Publicado: (2016)

Morphogenesis
por: Saunders, P T
Publicado: (1992)

Dynamic enlargement and mobilization of lipid droplets in pluripotent cells coordinate morphogenesis during mouse peri-implantation development
por: Mau, King Hang Tommy, et al.
Publicado: (2022)

Differences between homologous alleles of olfactory receptor genes require the Polycomb Group protein Eed
por: Alexander, Mary Kate, et al.
Publicado: (2007)

Plant morphogenesis /
por: Sinnott, Edmund W. (Edmund Ware), 1888-1958
Publicado: (1960)

Morphogenesis of the Skin
por: Nordlund, James J.
Publicado: (1977)

X Chromosomes Alternate between Two States prior to Random X-Inactivation
por: Mlynarczyk-Evans, Susanna, et al.
Publicado: (2006)

Genetic control of cellular morphogenesis in Müller glia
por: Charlton‐Perkins, Mark, et al.
Publicado: (2019)

Transnational law as a framework for law clinics
por: Kalantry, Sital, et al.
Publicado: (2021)

Folic Acid Rescues Valproic Acid-Induced Morphogenesis Inhibition in Neural Rosettes Derived From Human Pluripotent Stem Cells
por: Zhang, Xiao-zuo, et al.
Publicado: (2022)

Structural Determinants and Their Role in Cyanobacterial Morphogenesis
por: Springstein, Benjamin L., et al.
Publicado: (2020)

Facial Morphogenesis of the Earliest Europeans
por: Lacruz, Rodrigo S., et al.
Publicado: (2013)

MORPHOGENESIS OF THE COLLAGENOUS STROMA IN THE CHICK CORNEA
por: Trelstad, Robert L., et al.
Publicado: (1971)

Specification of the patterning of a ductal tree during branching morphogenesis of the submandibular gland
por: Walker, Janice L., et al.
Publicado: (2021)

Distributed automated manufacturing of pluripotent stem cell products
por: Shariatzadeh, Maryam, et al.
Publicado: (2019)

Feedback, Lineages and Self-Organizing Morphogenesis
por: Kunche, Sameeran, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_eam2d2vu98gbskup7t8d6eu0f1