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Prepatterning by RhoGEFs governs Rho GTPase spatiotemporal dynamics during wound repair

Like tissues, single cells are subjected to continual stresses and damage. As such, cells have a robust wound repair mechanism comprised of dynamic membrane resealing and cortical cytoskeletal remodeling. One group of proteins, the Rho family of small guanosine triphosphatases (GTPases), is critical...

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Detalles Bibliográficos
Autores principales: Nakamura, Mitsutoshi, Verboon, Jeffrey M., Parkhurst, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716286/
https://www.ncbi.nlm.nih.gov/pubmed/28923977
http://dx.doi.org/10.1083/jcb.201704145