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An excitable Rho GTPase signaling network generates dynamic subcellular contraction patterns

Rho GTPase-based signaling networks control cellular dynamics by coordinating protrusions and retractions in space and time. Here, we reveal a signaling network that generates pulses and propagating waves of cell contractions. These dynamic patterns emerge via self-organization from an activator–inh...

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Detalles Bibliográficos
Autores principales: Graessl, Melanie, Koch, Johannes, Calderon, Abram, Kamps, Dominic, Banerjee, Soumya, Mazel, Tomáš, Schulze, Nina, Jungkurth, Jana Kathrin, Patwardhan, Rutuja, Solouk, Djamschid, Hampe, Nico, Hoffmann, Bernd, Dehmelt, Leif, Nalbant, Perihan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716289/
https://www.ncbi.nlm.nih.gov/pubmed/29055010
http://dx.doi.org/10.1083/jcb.201706052