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An excitable Rho GTPase signaling network generates dynamic subcellular contraction patterns
Rho GTPase-based signaling networks control cellular dynamics by coordinating protrusions and retractions in space and time. Here, we reveal a signaling network that generates pulses and propagating waves of cell contractions. These dynamic patterns emerge via self-organization from an activator–inh...
Autores principales: | Graessl, Melanie, Koch, Johannes, Calderon, Abram, Kamps, Dominic, Banerjee, Soumya, Mazel, Tomáš, Schulze, Nina, Jungkurth, Jana Kathrin, Patwardhan, Rutuja, Solouk, Djamschid, Hampe, Nico, Hoffmann, Bernd, Dehmelt, Leif, Nalbant, Perihan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716289/ https://www.ncbi.nlm.nih.gov/pubmed/29055010 http://dx.doi.org/10.1083/jcb.201706052 |
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