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Proteinopathies and OXPHOS dysfunction in neurodegenerative diseases
Mitochondria participate in essential processes in the nervous system such as energy and intermediate metabolism, calcium homeostasis, and apoptosis. Major neurodegenerative diseases are characterized pathologically by accumulation of misfolded proteins as a result of gene mutations or abnormal prot...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716291/ https://www.ncbi.nlm.nih.gov/pubmed/29167179 http://dx.doi.org/10.1083/jcb.201709172 |