Bioequivalence study of two formulations of flupirtine maleate capsules in healthy male Chinese volunteers under fasting and fed conditions

AIM: This study developed a high-performance liquid chromatography–tandem mass spectrometry method to simultaneously determine the concentrations of flupirtine and its major active metabolite D-13223 in human plasma in order to assess the bioequivalence (BE) of two flupirtine maleate capsules among...

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Detalles Bibliográficos
Autores principales: Liu, Yanfang, Huo, Hua, Zhao, Zhibo, Hu, Wenli, Sun, Yujia, Tang, Yunbiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716300/
https://www.ncbi.nlm.nih.gov/pubmed/29238169
http://dx.doi.org/10.2147/DDDT.S149913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716300/
https://www.ncbi.nlm.nih.gov/pubmed/29238169
http://dx.doi.org/10.2147/DDDT.S149913

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