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Increased PKMζ activity impedes lateral movement of GluA2-containing AMPA receptors

Protein kinase M zeta (PKMζ), a constitutively active, atypical protein kinase C isoform, maintains a high level of expression in the brain after the induction of learning and long-term potentiation (LTP). Further, its overexpression enhances long-term memory and LTP. Thus, multiple lines of evidenc...

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Detalles Bibliográficos
Autores principales: Yu, Nam-Kyung, Uhm, Heesoo, Shim, Jaehoon, Choi, Jun-Hyeok, Bae, Sangsu, Sacktor, Todd Charlton, Hohng, Sungchul, Kaang, Bong-Kiun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716381/
https://www.ncbi.nlm.nih.gov/pubmed/29202853
http://dx.doi.org/10.1186/s13041-017-0334-7