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Sensitive detection of HIV-1 resistance to Zidovudine and impact on treatment outcomes in low- to middle-income countries

BACKGROUND: Thymidine analogs, namely AZT (Zidovudine or Retrovir™) and d4T (Stavudine or Zerit™) are antiretroviral drugs still employed in over 75% of first line combination antiretroviral therapy (cART) in Kampala, Uganda despite aversion to prescribing these drugs for cART in high income countri...

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Detalles Bibliográficos
Autores principales: Gibson, Richard M., Nickel, Gabrielle, Crawford, Michael, Kyeyune, Fred, Venner, Colin, Nankya, Immaculate, Nabulime, Eva, Ndashimye, Emmanuel, Poon, Art F. Y., Salata, Robert A., Kityo, Cissy, Mugyenyi, Peter, Quiñones-Mateu, Miguel E., Arts, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716384/
https://www.ncbi.nlm.nih.gov/pubmed/29202874
http://dx.doi.org/10.1186/s40249-017-0377-0